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Tricals - The highway towards a cure
National ALS Clinic and Research Group, Beaumont Hospital Dublin

Trinity College Dublin

Ireland - Dublin

The National ALS service is co-located between the National Neuroscience Centre (Beaumont) and the Academic Unit of Neurology at Trinity College Dublin. The service provides multidisciplinary care to patients across Ireland, and engages in applied clinical research, along with Phase 1,2,3 and 4 clinical trials.

The National ALS clinical service provides full multidisciplinary care to those with ALS/MND across Ireland from diagnosis to end of life, and facilitates in-clinic and home visits. The service supports the national population based Register for ALS/MND, in operation since 1994. The clinical service at Beaumont Hospital is closely aligned with the ALS/MND Research group, at the Academic Unit of Neurology in Trinity College Dublin, enabling high quality clinical and applied ALS research including the international PRECISION ALS project. Both clinical and research programmes are led by Prof Ola Hardiman. The national ALS/MND service is supported by the charity Research Motor Neurone, and works closely with patient support group (Irish Motor Neurone Disease Association). The Irish ALS/MND programme participates in multiple clinical trials, operating at clinical research facilities at Beaumont and St James’s Hospitals, and open to all patients on the island of Ireland.

 

Specialists in this centre

Orla Hardiman

Professor of Neurology

Niamh Ní Óbáin

Clinical Trials Research Manager

Amina Coffey

Neurology Fellow

Sarah Darcy

Neurology Research Fellow

Robert McFarlane

Neurology Research Fellow

Sinead Maguire

Neurology Research Fellow

Toyosi Atoyebi

Clinical Nurse Manager & Specialist

Location

Hospital Rd, 9QRH+4F,Dublin,Ireland

Contact

Current trials in this centre

Closed for participation

DAZALS

Phase 2
Industry
No

In this study, an investigational oral drug named dazucorilant (also called CORT113176) is being studied in people living with ALS.

More about this trial

Closed for participation

FUSION

Phase 3
Industry
FUS

This study investigates the safety & efficacy of the study drug ‘ION363’ for the treatment of ALS caused by mutations in the FUS gene.

More about this trial

Closed for participation

Lighthouse 2

Phase 3
IIT
No

The Lighthouse 2 study is a phase 3 clinical trial in which we will investigate the efficacy of the drug Triumeq.

More about this trial

Archived

TUDCA-ALS

Phase 3
IIT
No

This trial will evaluate the efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment for people with ALS.

More about this trial

Archived

PHOENIX

Phase 3
Industry
No

Amylyx Pharmaceuticals Inc is conducting a phase 3 trial to determine the safety and efficacy of their compound 'AMX0035'.

More about this trial

Archived

ADORE

Phase 3
Industry
No

Ferrer is conducting a phase 3 trial to evaluate the safety and potential efficacy of FNP122 for people with ALS.

More about this trial

Archived

APL2-ALS-206 trial

Phase 2
Industry
No

In this phase 2 study, we are investigating the safety and efficacy of the drug pegcetacoplan for the treatment of ALS.

More about this trial

Archived

COURAGE-ALS

Phase 3
Industry
No

In the COURAGE-ALS study, we are investigating the efficacy and safety of the drug ‘reldesemtiv’ for the treatment of ALS.

More about this trial

Archived

ALXN1210-ALS-308 trial

Phase 3
Industry
No

This study is designed to test the efficacy and safety of intravenous Ravulizumab in patients with ALS.

More about this trial

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