Amyotrophic Lateral Sclerosis Unit in Vall d’Hebron Hospital is a multidisciplinary unit with broad experience in the field, recognised as National and European Reference Centre in Neuromuscular disorders. In last 20 years we have participated in diverse phase 2 and 3 clinical trials.
Moreover, our laboratory in the Neuromuscular Disorders Unit of the Neurology Department, has a twenty-year history of providing clinical care and research in Amyotrophic Lateral Sclerosis (ALS) and other motor neuron diseases (hereditary spastic paraplegias, postpolio syndrome, Hirayama’s disease, spinal muscular atrophies), myasthenia gravis, genetically determined myopathies, and peripheral neuropathies. Our main research lines are Molecular Mechanisms of ALS, Genetic Mutations in Familial ALS, including predisposing or modifying gene factors, and the role of signaling genes in the pathogenesis of familial and sporadic forms of ALS. Our work also involves searching for effective biomarkers in blood and CSF.
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